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Recombinant Feline Cytochrome P450 1A1 (CYP1A1)
Product Overview
BioVenic's Recombinant Feline Cytochrome P450 1A1 (CYP1A1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 58.7 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
In felines, cytochrome P450 1A1 (CYP1A1) is a key monooxygenase enzyme involved in the metabolism of xenobiotics, including polycyclic aromatic hydrocarbons and heterocyclic amines. It is expressed in various tissues, particularly in extrahepatic sites like the lungs, kidneys, intestines, and skin, and its expression is inducible by the aryl hydrocarbon receptor (AhR). CYP1A1 plays important roles in drug metabolism, activation of procarcinogens, and antioxidant responses, and genetic polymorphisms in CYP1A1 may influence cancer susceptibility.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.