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Recombinant Mouse Bone Morphogenetic Protein Receptor Type-1A (BMPR1a), C-Fc-His

Cat. No.AP2C770

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Bone Morphogenetic Protein Receptor Type-1A (BMPR1a), C-Fc-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 60.1 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 60.1 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse Bone Morphogenetic Protein Receptor Type-1A, or BMPR1a, is a receptor involved in bone development and tissue repair. In mouse studies, BMPR1a is explored for its potential applications in bone disease treatment and tissue engineering. This receptor is a key component of the BMP signaling pathway, which regulates osteogenesis, chondrogenesis, and other developmental processes. Mutations in BMPR1a have been associated with various skeletal disorders, including juvenile polyposis syndrome and hereditary hemorrhagic telangiectasia. By understanding the mechanisms of BMPR1a signaling, researchers aim to develop novel therapeutic agents that can modulate this pathway to promote bone healing and tissue regeneration. Additionally, BMPR1a is being investigated for its role in cancer progression, as dysregulation of BMP signaling can influence tumor growth and metastasis, offering potential targets for anticancer therapies.

Protein Mouse Bone Morphogenetic Protein Receptor Type-1A (BMPR1a)
Protein Synonym Activin receptor-like kinase 3; BMP-2; BMP-4 receptor; Serine/threonine-protein kinase receptor R5; SKR5
Gene ID 12166
UniProt ID P36895

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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