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Recombinant Bovine Protein S100-A12 (S100A12), N-His
Product Overview
BioVenic's Recombinant Bovine Protein S100-A12 (S100A12), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 14.2 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine S100 calcium binding protein A12 (S100A12) is a member of the S100 protein family, known for its calcium-binding ability and involvement in various cellular processes. In cattle, S100A12 is predominantly secreted by granulocytes and plays a significant role in the innate immune response. It contributes to inflammation and immune surveillance, often associated with conditions like mastitis. The protein's extracellular activities include acting as a chemoattractant and modulating intracellular signaling pathways, leading to cytokine production and oxidative stress responses. It's also been identified as a valuable serum inflammatory marker in Bovine health assessments.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.