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Recombinant Canine Oral Papillomavirus Protein E7 (E7)
Product Overview
BioVenic's Recombinant Canine Oral Papillomavirus Protein E7 (E7) is a recombinant protein expressed from Yeast. Its predicted molecular weight is 10.8 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Canine oral papillomavirus protein E7 (E7) is an oncoprotein that promotes cell division by degrading retinoblastoma protein (pRb), a key regulator of the cell cycle. In veterinary medicine, E7 is crucial for understanding the progression of papillomas to neoplasia in dogs. Its role in disrupting cell cycle control makes it a potential biomarker for neoplastic transformation and a target for therapeutic interventions. Additionally, E7-induced degradation of pRb leads to increased p16 expression, which can be detected via immunohistochemistry to indicate papillomavirus-associated neoplasia.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.