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Recombinant Canine Uromodulin (UMOD)
Product Overview
BioVenic's Recombinant Canine Uromodulin (UMOD) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 13.8 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine Uromodulin, also known as Tamm-Horsfall protein, is a glycoprotein that is the most abundant protein in the urine of mammals, including dogs. It plays a role in regulating salt reabsorption, cation homeostasis, and is implicated in hypertension, acute kidney injury, chronic kidney disease, urinary defense, systemic inflammation and stress, immunomodulation, and kidney stone disease. Uromodulin exists in both polymerized and nonpolymerized forms, which are released through distinct cellular pathways and may have different functions in the renal interstitium and circulation.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.