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Recombinant Chicken Metalloproteinase Inhibitor 2 (TIMP2), N-His

Cat. No.AP1C371

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Chicken Metalloproteinase Inhibitor 2 (TIMP2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 25.4 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Chicken
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 25.4 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Target Information

Chicken metalloproteinase inhibitor 2 (TIMP2) functions as an inhibitor of matrix metalloproteinases (MMPs), enzymes that play a significant role in the regulation of the extracellular matrix remodeling. In chickens, TIMP2 is crucial for preserving the equilibrium between tissue formation and breakdown. It is involved in critical biological processes such as embryonic development, tissue repair, and the formation of new blood vessels. Additionally, TIMP2 helps in guarding against diseases that result from MMP misregulation, including arthritis and specific types of cancer.

Protein Chicken Metalloproteinase Inhibitor 2 (TIMP2)
Protein Synonym Tissue inhibitor of metalloproteinases 2 (TIMP-2)
Gene ID 374178
UniProt ID O42146

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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