Recombinant Chicken Neurofilament Medium Polypeptide (NEFM)

Chicken Neurofilament Medium Polypeptide (NEFM) is a key structural protein in the nervous system of chickens, specifically found in nerve fibers and axons. It is part of the neurofilament family, which includes three intermediate filament proteins: light (NF-L), medium (NF-M), and heavy (NF-H). These proteins play a crucial role in maintaining the caliber and structural integrity of neurons, ensuring proper signal transmission and nerve function. In chickens, NEFM helps sustain the proper diameter of axons, which is essential for efficient electrical signal conduction. This is particularly important in the peripheral and central nervous systems, where accurate and rapid transmission of signals is vital for coordination, movement, and sensory functions. Researchers study NEFM levels in chicken samples such as serum, plasma, and tissue lysates to gain insights into neurofilament dynamics and related neurological disorders. Changes in NEFM levels have been associated with various neurodegenerative diseases, and understanding its role can potentially identify new therapeutic targets for improving chicken health and productivity.