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Recombinant Chicken Tissue Necrosis Factor-Alpha (TNF-alpha), N-His

Cat. No.AP1C344

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Chicken Tissue Necrosis Factor-Alpha (TNF-alpha), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 38.1 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Chicken
Expression System E.coli
Purity >95% (SDS-PAGE)
Predicted Molecular Weight 38.1 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Target Information

In chickens, interleukin-18 (IL18) primarily functions in the immune system, particularly in regulating inflammatory responses and immune reactions. IL18 activates natural killer (NK) cells and T cells, enhancing the body's immune defense capabilities. Additionally, IL18 regulates cytokine production, promoting the secretion of interferon-γ (IFN-γ), thereby enhancing cell-mediated immune responses. In the chicken intestine, IL18 helps maintain the integrity of the intestinal mucosa, preventing pathogen invasion. These functions indicate that IL18 plays an important role in immune regulation and disease defense in chickens.

Protein Chicken Tissue Necrosis Factor-Alpha (TNF-alpha)
UniProt ID F1DFK9

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 19 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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