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Recombinant Bovine Insulin-Like Growth Factor-Binding Protein 4 (IGFBP4), N-His
Product Overview
BioVenic's Recombinant Bovine Insulin-Like Growth Factor-Binding Protein 4 (IGFBP4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine insulin like growth factor binding protein 4 (IGFBP4) is a member of the insulin-like growth factor binding protein family. IGFBP4 is predominantly involved in regulating the bioavailability and activity of insulin-like growth factors (IGFs), which are crucial for cell growth, differentiation, and DNA synthesis. This protein can inhibit IGF actions in various in vitro models and is thought to play a role in tissue development, particularly in gonads and bone. IGFBP4 is also subject to hormonal regulation, with treatments like growth hormone, vitamin D3, and PTH enhancing its serum levels, while estradiol decreases them. In cattle, IGFBP4 may be important for growth traits and could be a factor in reproductive biology and overall health .
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.