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Recombinant Bovine Pleiotrophin (PTN)

Cat. No.AP9C388

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Pleiotrophin (PTN) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 16.8 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity >95% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 16.8 kDa
Molecular Weight 18 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Bovine pleiotrophin is a multifunctional protein that belongs to the heparin-binding growth factor family. It is known for its role in various biological processes such as cell adhesion, migration, survival, growth, and differentiation. Pleiotrophin is an 18 kDa protein that is highly conserved across different species, including cattle, and is involved in neural development, tumor growth, and tissue repair. In cattle, Pleiotrophin has been associated with the modulation of chondrocyte phenotype and the regulation of limb development and growth. It is also implicated in the maintenance of hematopoietic stem cells, adipocyte differentiation, and endothelial cell migration. The protein's expression patterns suggest its importance in fetal development, with abundant mRNA present in fetal cartilage but at significantly lower levels in adult cartilage.

Protein Bovine Pleiotrophin (PTN)
Protein Synonym HARP; HBGF8; HBNF; NEGF1; Heparin Binding Growth Factor 8; Neurite Growth-Promoting Factor 1; Heparin Affin Regulatory Peptide; Heparin Binding Growth Associated Molecule
Gene ID 280904
UniProt ID P21782

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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