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Recombinant Chicken Transcription Factor Jun (JUN)
Product Overview
BioVenic's Recombinant Chicken Transcription Factor Jun (JUN) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 34.4 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Chicken Transcription Factor Jun (JUN) is a member of the AP-1 transcription factor complex, which plays a crucial role in regulating gene expression in response to various stimuli. JUN influences cell proliferation, differentiation, and apoptosis by binding to specific DNA sequences and modulating the transcription of target genes. Research indicates that JUN can promote female differentiation in chickens by inhibiting Smad2, affecting the expression of genes like DMRT1 and SOX9 in embryonic gonads. Additionally, JUN interacts with other proteins such as FOS to form dimers, enhancing its transcriptional activity. The expression patterns of JUN and other Fos/Jun family members vary across different tissues and developmental stages, highlighting its diverse roles in chicken biology. Studies on JUN's promoter region and transcriptional regulation provide insights into its mechanistic roles in cellular processes.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.