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Recombinant Equine Transforming Growth Factor Beta-1 Proprotein (TGFB1), N-His-GST

Cat. No.AP9C978

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Equine Transforming Growth Factor Beta-1 Proprotein (TGFB1), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 42.8 kDa. The purity is>97% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Equine
Expression System E.coli
Purity >97% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 42.8 kDa
Molecular Weight 43.0 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Equine transforming growth factor beta-1 proprotein (TGF-β1) is a multifunctional cytokine that is synthesized by almost all cells and plays a significant role in cell proliferation, growth, differentiation, and cell movement. It is secreted as an inactive peptide, forming part of a latent complex, and upon activation, it binds to cell-surface TGF-β type I and type II receptors, which are transmembrane serine/threonine kinases. TGF-β1 has immunomodulatory effects and profibrogenic effects, playing a driving role in development, fibrosis, and cancer.

Protein Equine Transforming Growth Factor Beta-1 Proprotein (TGFB1)
Protein Synonym TGF-B1; CED; DPD1; LAP; Camurati-Engelmann Disease; Latency-associated peptide
Gene ID 100033900
UniProt ID O19011

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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