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Recombinant Mouse Integrin-Binding Sialoprotein (Ibsp), C-His
Product Overview
BioVenic's Recombinant Mouse Integrin-Binding Sialoprotein (Ibsp), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 35.7 kDa. The purity is>90%.
Specifications
Target Information
Mouse Integrin-Binding Sialoprotein (Ibsp), also known as bone sialoprotein, is a glycosylated phosphoprotein expressed in mineralized tissues such as bone and teeth. Ibsp binds to hydroxyapatite crystals and integrins on cell surfaces, facilitating cell adhesion and mineralization processes. In mice, Ibsp is involved in the formation and mineralization of bone matrix, with mutations in the Ibsp gene leading to skeletal abnormalities and defective mineralization. Research on Ibsp in mice has provided insights into its role in bone development, repair, and diseases such as osteoporosis and osteogenesis imperfecta, highlighting its importance as a therapeutic target for bone-related disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.