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Recombinant Bovine C-C Motif Chemokine 5 (CCL5)
Product Overview
BioVenic's Recombinant Bovine C-C Motif Chemokine 5 (CCL5) is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Bovine CCL5, also known as regulated on activation, normal T cell expressed and secreted (RANTES), is a pro-inflammatory chemokine that belongs to the CC chemokine family. It plays a significant role in the immune response by attracting various immune cells, including monocytes, T cells, and eosinophils, to sites of inflammation. In cattle, CCL5 is crucial for immune cell trafficking and activation, contributing to the body's defense against infections. It is involved in the modulation of inflammation and bone metabolism, and has been implicated in the pathogenesis of diseases such as mastitis and respiratory infections. The expression of CCL5 in Bovine macrophages can be up-regulated in response to bacterial challenges, indicating its role in the innate immune response.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.