Recombinant Mouse Pro-cathepsin H (Ctsh), C-His

Mouse Pro-cathepsin H (Ctsh) is a lysosomal protease synthesized as a proenzyme that requires proteolytic activation to become active. Ctsh belongs to the cysteine protease family and is involved in intracellular protein degradation and turnover. In mice, Ctsh is expressed in various tissues, including the liver, kidney, and brain, and its expression is regulated by nutritional and hormonal factors. Research on Ctsh in mice has shown its involvement in the degradation of specific substrates, such as insulin-like growth factor-binding proteins, and its potential role in regulating cell growth and differentiation. Ctsh has also been implicated in pathological processes such as cancer progression and neurodegeneration, highlighting its significance in both physiological and pathological contexts.