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Recombinant Swine Insulin-Like Growth Factor-Binding Protein 2 (IGFBP2)
Product Overview
BioVenic's Recombinant Swine Insulin-Like Growth Factor-Binding Protein 2 (IGFBP2) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 38.4 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Swine insulin-like growth factor binding protein 2 (IGFBP2) is a protein that binds to insulin-like growth factors (IGFs), playing a role in regulating their bioavailability and activity. IGFBP2 can act both in an IGF-dependent manner, by modulating IGF signaling, and in an IGF-independent manner, by interacting with cell surface receptors and the extracellular matrix. It is involved in a variety of cellular processes including cell cycle regulation, insulin and glucose metabolism, and angiogenesis.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Guidry, Clyde. et al. Isolation and characterization of vitreous insulin-like growth factor binding proteins. Investigative ophthalmology & visual science 2011, 52: 1 303-9. 5