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Recombinant Swine Platelet Factor 4 (PF4), N-His
Product Overview
BioVenic's Recombinant Swine Platelet Factor 4 (PF4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 16.7 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Swine platelet factor 4 (PF4) is a small chemokine that is stored in platelet alpha-granules and rapidly secreted upon activation. It is involved in coagulation, tissue repair, and innate immune response. PF4 neutralizes the effects of heparin on endothelial cells, thereby promoting coagulation, and also inhibits endothelial cell migration, proliferation, and angiogenesis. It is known to bind to growth factors like FGF and block VEGF signaling, playing a role in anti-angiogenic effects.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.