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Bovine Asymmetrical Dimethylarginine (ADMA) ELISA Kit-Competitive

Cat. No.EK1F296

Product TypeAnimal Immunoassay Kits

Size 96T

Product Overview

BioVenic Bovine Asymmetrical Dimethylarginine (ADMA) ELISA Kit-Competitive is designed for the quantitative determination of Bovine Asymmetrical Dimethylarginine (ADMA) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive
Specificity The assay kit is specific for Bovine ADMA.
Target Species Bovine
Species Reactivity Bovine
Detection Range 15.63-1000 ng/mL
Sensitivity 4.51 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 120 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Asymmetric dimethylarginine (ADMA), an endogenous competitive inhibitor of nitric oxide synthase, is associated with impaired endothelial dysfunction such as chronic heart failure, hypertension, diabetes, and pulmonary hypertension. Research has shown that ADMA can inhibit the proliferation of bovine retinal capillary endothelial cells (BRCECs), increase intracellular ROS generation, increase cell permeability and, in BRCECs, decrease the levels of the tight junction protein occludin and increase ICAM-1 expression.

Target/Biomarker Bovine ADMA
Target Synonym N,N-Dimethylarginine; NG,NG-Dimethylarginine dihydrochloride; Asymmetric Dimethylarginine

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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