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Bovine Proteinase-Activated Receptor 1 (F2R) ELISA Kit-Sandwich

Name: Bovine Proteinase-Activated Receptor 1 (F2R) ELISA Kit-Sandwich
SKU: EK11F688
Rating: 5 (1 reviews)

Cat. No.EK11F688

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Proteinase-Activated Receptor 1 (F2R) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Proteinase-Activated Receptor 1 (F2R) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine F2R.

Target Species Bovine

Species Reactivity Bovine

Detection Range 0.78-50 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Bovine Proteinase-Activated Receptor 1 is encoded by the F2R gene in cattle. It is a G protein-coupled receptor and one of four protease-activated receptors involved in the regulation of thrombotic response. It plays an important role in the development of diabetic nephropathy and it might therefore be an attractive therapeutic target to pursue in diabetic nephropathy. It plays a crucial role in cellular responses to thrombin and related proteases.

Target/Biomarker Bovine F2R

Target Synonym coagulation factor II thrombin receptor; PAR1; proteinase-activated receptor 1; PAR-1; protease-activated receptor 1; thrombin receptor

Gene ID 526585

UniProt ID A7YY44

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Waasdorp, M. et al. Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice. Scientific reports. 2016, 6: 33030.