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Bovine Thimet Oligopeptidase (THOP1) ELISA Kit-Sandwich

Cat. No.EK11F550

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Bovine Thimet Oligopeptidase (THOP1) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Thimet Oligopeptidase (THOP1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine THOP1.
Target Species Bovine
Species Reactivity Bovine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Thimet Oligopeptidase 1 (THOP1) is a metalloendopeptidase found in the brains of Alzheimer patients. It can cleave a synthetic peptide encompassing the amino-terminus of amyloid β-peptide and generate amyloidogenic fragments from recombinant human amyloid precursor protein (APP). THOP1 is involved in the metabolism of neuropeptides under 20 amino acids long. Bovine Thimet Oligopeptidase is encoded by the THOP1 gene in cattle. It is a metallopeptidase ubiquitously distributed in mammalian tissues.

Target/Biomarker Bovine THOP1
Target Synonym thimet oligopeptidase 1; thimet oligopeptidase; endopeptidase EC3.4.24.15
Gene ID 510889
UniProt ID Q1JPJ8

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Ferro, E. S. et al. Thimet Oligopeptidase Biochemical and Biological Significances: Past, Present, and Future Directions. Biomolecules. 2020, 10: 1229.
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