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Guinea Pig Angiotensin I Converting Enzyme (ACE) ELISA Kit-Sandwich

Cat. No.EK3F109

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Guinea Pig Angiotensin I Converting Enzyme (ACE) ELISA Kit-Sandwich is designed for the quantitative determination of Guinea Pig ACE in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Guinea Pig ACE.
Target Species Guinea Pig
Species Reactivity Guinea Pig
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Angiotensin-converting enzyme (ACE) plays a pivotal role in the renin-angiotensin system (RAS), which is crucial for controlling blood pressure by managing the body's fluid volume. This enzyme transforms the hormone angiotensin I into the active vasoconstrictor angiotensin II. It achieves this by hydrolyzing peptides, removing a dipeptide from their C-terminus. Specifically, ACE converts the inactive decapeptide angiotensin I into the octapeptide angiotensin II through the removal of the dipeptide His-Leu. Guinea pigs are used in cardiovascular research, and ACE's role in regulating blood pressure is investigated. Studies have examined the effects of ACE inhibitors on guinea pig cardiovascular function.

Target/Biomarker Guinea Pig ACE
Target Synonym Angiotensin-converting enzyme; ACE; Dipeptidyl carboxypeptidase I; Kininase II; Angiotensin-converting enzyme, soluble form; ACE; DCP; DCP1; Angiotensin I Converting Enzyme

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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