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Guinea Pig Tissue Inhibitors of Metalloproteinase 2 (TIMP2) ELISA Kit-Sandwich
Product Overview
BioVenic Guinea Pig Tissue Inhibitors of Metalloproteinase 2 (TIMP2) ELISA Kit-Sandwich is designed for the quantitative determination of Guinea Pig TIMP2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Tissue inhibitor of metalloproteinases 2 (TIMP2) belongs to the TIMP gene family and is believed to act as a metastasis suppressor. TIMP2 serves dual functions as both an inhibitor and activator of metalloproteinases (MMPs). TIMP2 plays a critical role in regulating the activation of pro-MMP2 on the cell surface. It can form a complex with pro-MMP2 and MT1-MMP, which facilitates the activation of MMP2. Studies have indicated that transforming growth factor-beta reduces the expression of TIMP-2 mRNA in guinea pig lung fibroblasts, while various other stimuli do not influence its expression.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.