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Mouse Anti-Bovine Huntingtin-Interacting Protein (HIP) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine huntingtin-interacting protein. It can be applied to WB, IHC, IF and ICC assays of bovine huntingtin-interacting protein.
Specifications
Target Information
HIP, also known as huntingtin-interacting protein, is a multifunctional protein that plays a significant role in various cellular processes, including endocytosis, protein trafficking, and signal transduction. It is highly conserved across species and is characterized by its ability to interact with a wide range of binding partners, including the protein huntingtin, which is associated with huntington's disease. The interaction of HIP with huntingtin is particularly important, as it is believed to modulate the aggregation and clearance of mutant huntingtin proteins, which are implicated in the pathogenesis of Huntington's disease. Additionally, HIP has been implicated in the regulation of cell cycle progression and apoptosis, further highlighting its importance in maintaining cellular homeostasis.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Hackam, Abigail S., et al. "Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain." Journal of Biological Chemistry 275.52 (2000): 41299-41308.