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Mouse Anti-Porcine T-Complex Protein 1 Subunit Beta (CCT2) Monoclonal Antibody

Cat. No.VD8N349

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for T-complex protein 1 subunit beta. It is affinity purified by protein A. It can be applied to WB, IF and ELISA assays of T-complex protein 1 subunit beta.

Specifications

Application WB; IF; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G8N2
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity T-Complex Protein 1 Subunit Beta
Isotype IgG1
Immunogen Recombinant protein of T-complex protein 1 subunit beta
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine T-Complex Protein 1 Subunit Beta (CCT2), also known as the beta subunit of the chaperonin-containing TCP-1 (CCT) complex, is a crucial component of the CCT chaperonin system. This complex plays a vital role in assisting the folding of actin and tubulin, two major components of the cytoskeleton, which are essential for maintaining cell shape, facilitating intracellular transport, and cell division. CCT2, as part of the CCT complex, is highly conserved across species, reflecting its fundamental importance in cellular physiology. It contributes to the folding and assembly of newly synthesized proteins, particularly those with complex structures, and helps in the refolding of misfolded proteins, thus preventing the aggregation that can lead to cellular stress and disease.

Target T-Complex Protein 1 Subunit Beta
Target Synonym 99D8.1; CCT beta
Gene ID 100157776
UniProt ID D0G0C8

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Chen, Hui, et al. "Chaperonin-containing T-complex protein 1 subunit ζ serves as an autoantigen recognized by human Vδ2 γδ T cells in autoimmune diseases." Journal of Biological Chemistry 291.38 (2016): 19985-19993.
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