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Mouse Anti-Canine Respiratory Coronavirus (CRCoV) Nucleoprotein Monoclonal Antibody

Cat. No.VD7N224

Product TypeVeterinary Antibodies

Size 100 µg

Product Overview

BioVenic mouse monoclonal antibody is specific for canine respiratory coronavirus nucleoprotein. It is affinity purified by protein A. It can be applied to ELISA, IFA and WB assays of canine respiratory coronavirus nucleoprotein.

Specifications

Application ELISA; IFA; WB
Clonality Monoclonal
Classification Primary Antibody
Clone G1N29
Host Mouse
Target Species Virus
Species Reactivity Canine
Specificity Canine Respiratory Coronavirus Nucleoprotein
Isotype IgG1
Immunogen Recombinant canine respiratory coronavirus nucleoprotein
Purification Protein A Purified
Purity > 90%
Conjugation Unconjugated
Buffer 0.02µM Phosphate Buffered Saline, pH 7.4
Physical State Liquid

Target Information

Canine respiratory coronavirus (CRCoV) is a pathogen that can lead to respiratory infections in dogs. The nucleoprotein (NP) of CRCoV is an integral component of the virus, playing a central role in the packaging of the viral RNA genome into the nucleocapsid. The NP is involved in various steps of the viral replication cycle and is essential for the assembly of new virions. The NP is a potential target for antiviral therapies against CRCoV due to its indispensable function in the viral life cycle. Inhibiting the NP could disrupt the replication and assembly processes, thereby limiting the spread of the virus within the host. Additionally, the NP is an immunogenic protein that can stimulate an immune response, making it a candidate for diagnostic assays and vaccine development.

Target Canine Respiratory Coronavirus Nucleoprotein
Taxonomy ID 215681
UniProt ID D0EY89

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 24 months). Avoid exposure to light. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Colitti, Barbara, et al. "Pulmonary fibrosis in a dog as a sequela of infection with Severe Acute Respiratory Syndrome Coronavirus 2? A case report." BMC veterinary research 18.1 (2022): 111.
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