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Rabbit Anti-Equine IgG (H+L) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for equine IgG (H+L). It can be applied to ICC, IHC and WB assays of equine IgG (H+L).
Specifications
Target Information
Equine IgG (H+L) refers to the immunoglobulin G found in horses, which is composed of two heavy chains and two light chains. Horses have a unique immunoglobulin profile, with seven IgG subclasses identified, denoted as IgG1 to IgG7. These subclasses vary in their effector functions, which has implications for vaccine strategies and therapeutic applications. The equine IgG subclasses exhibit different capabilities in terms of eliciting immune responses. For instance, IgG1, IgG3, IgG4, IgG5, and IgG7 can interact with Fc receptors on effector cells and activate the complement system via the classical pathway, suggesting their importance in immune defense.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid exposure to light. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Lewis, Melanie J., et al. "The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies." Molecular immunology 45.3 (2008): 818-827.