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Rabbit Anti-Fragile X Mental Retardation Protein (FMRP) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for fragile X mental retardation protein. It can be applied to IHC and WB of fragile X mental retardation protein.
Specifications
Target Information
The fragile X mental retardation protein (FMRP) is a critical regulatory protein involved in the development and function of the nervous system. FMRP plays a significant role in the control of protein synthesis, particularly in the regulation of the translation of specific messenger RNAs (mRNAs) in neurons. The absence or dysfunction of FMRP is associated with Fragile X Syndrome (FXS), the leading inherited cause of intellectual disability and autism spectrum disorders. FMRP is considered a target for therapeutic intervention in FXS due to its pivotal role in neuronal development and synaptic plasticity. Targeting FMRP involves strategies aimed at restoring its normal function or compensating for its loss.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Smidak, Roman, et al. "Reduced levels of the synaptic functional regulator FMRP in dentate gyrus of the aging sprague-dawley rat." Frontiers in aging neuroscience 9 (2017): 384.