Mouse Anti-Canine Endothelial Lipase (LIPG) Monoclonal Antibody

Canine endothelial lipase (EL) is an enzyme that plays a significant role in lipoprotein metabolism, particularly in the metabolism of high-density lipoproteins (HDL) in circulation. It is expressed in various tissues, including placenta, thyroid, liver, lung, kidney, ovary, and testes. EL shares closer genetic resemblance with hepatic and lipoprotein lipases compared to pancreatic lipase and has relatively high phospholipase activity. The enzyme is important for the metabolism of HDL in circulation and is involved in the hydrolysis of triglycerides within lipoproteins into free fatty acids, mono- and diglycerides, and glycerol. Understanding the role of EL in dogs can provide insights into lipid metabolism and its potential impact on cardiovascular and metabolic health, making it a significant target for therapeutic interventions in veterinary medicine.