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Mouse Anti-Porcine Calbindin 2 (CALB2) Monoclonal Antibody-[HRP]
Product Overview
BioVenic mouse monoclonal antibody is specific for calbindin 2. It is affinity purified by protein G. It can be applied to WB assay of calbindin 2.
Specifications
Target Information
Porcine calbindin 2, also known as calbindin-D28k, is a vitamin D-dependent calcium-binding protein that is prevalent in the central nervous system, particularly in the hippocampus and the intestine. This protein is renowned for its role in calcium homeostasis, where it buffers and transports calcium ions within neurons, thereby contributing to the regulation of synaptic transmission and memory formation. In pigs, calbindin 2 may serve as a crucial factor in maintaining neuronal health and could be implicated in the resilience to stress-induced memory deficits. The protein's regulation of calcium signaling pathways positions it as a potential therapeutic target for neurodegenerative diseases and conditions where calcium homeostasis is compromised. Understanding the function of calbindin 2 in pigs can offer insights into its role in human health and disease, highlighting its significance in both veterinary and medical research.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid exposure to light.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Stevenson, Leanne, et al. "Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway." PloS one 6.5 (2011): e20276.