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Mouse Anti-Porcine Calbindin 2 (CALB2) Monoclonal Antibody-[HRP]

Cat. No.VD10N22

Product TypeAnimal-targeted Antibodies

Size 100uL

Product Overview

BioVenic mouse monoclonal antibody is specific for calbindin 2. It is affinity purified by protein G. It can be applied to WB assay of calbindin 2.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone O11N22
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Calbindin 2
Isotype IgG1
Immunogen Recombinant protein of calbindin 2
Purification Protein G Purified
Concentration 1000 μg/mL
Conjugation HRP
Preservative and Stabilizer 0.05% Proclin 300
Buffer Phosphate Buffered Saline with 50% Glycerol and 0.5% Bovine Serum Albumin, pH 7.3
Physical State Liquid

Target Information

Porcine calbindin 2, also known as calbindin-D28k, is a vitamin D-dependent calcium-binding protein that is prevalent in the central nervous system, particularly in the hippocampus and the intestine. This protein is renowned for its role in calcium homeostasis, where it buffers and transports calcium ions within neurons, thereby contributing to the regulation of synaptic transmission and memory formation. In pigs, calbindin 2 may serve as a crucial factor in maintaining neuronal health and could be implicated in the resilience to stress-induced memory deficits. The protein's regulation of calcium signaling pathways positions it as a potential therapeutic target for neurodegenerative diseases and conditions where calcium homeostasis is compromised. Understanding the function of calbindin 2 in pigs can offer insights into its role in human health and disease, highlighting its significance in both veterinary and medical research.

Target Calbindin 2
Target Synonym 29 kDa calbindin
Gene ID 100127479
UniProt ID A0A2K6D5Z2

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid exposure to light.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Stevenson, Leanne, et al. "Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway." PloS one 6.5 (2011): e20276.
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