This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant African Swine Fever Virus Cysteine Protease S273R, N-His
Product Overview
BioVenic's Recombinant African Swine Fever Virus Cysteine Protease S273R, N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 33.7 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
African swine fever virus cysteine protease S273R (pS273R) is a crucial enzyme involved in the processing of viral polyproteins, which is essential for the maturation and infectivity of the virus particle. It belongs to the SUMO-1 cysteine protease family and plays a significant role in virus replication by catalyzing the maturation of pp220 and pp62 polyprotein precursors into core shell matrix proteins. Furthermore, pS273R has been identified as an antagonist of type I interferon (IFN), highlighting its role in immune evasion by inhibiting JAK-STAT signaling triggered by viral infections. This protein's function is vital in veterinary medicine for understanding the virus's life cycle, its mechanisms of immune evasion, and for developing strategies to control ASFV infection and vaccine development.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.