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Recombinant Feline Immunodeficiency Virus Envelope Glycoprotein gp150 (env)

Cat. No.VG2C142

Product TypeVeterinary Antigens

Size

Product Overview

BioVenic's Recombinant Feline Immunodeficiency Virus Envelope Glycoprotein gp150 (env) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 97.9 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Virus
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 97.9 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 5%-50% glycerol

Target Information

Feline immunodeficiency virus envelope glycoprotein gp150 (Env) is a critical component of the FIV virus, mediating viral entry by binding to host receptors such as CD134. It is highly variable and immunogenic, making it a key target for neutralizing antibodies. In veterinary medicine, gp150 is used to develop diagnostic assays and vaccines. However, its high variability can complicate vaccine efficacy. Additionally, the signal peptide of Env acts as a tetherin antagonist, facilitating viral release from host cells. Understanding gp150's role in viral entry and immune evasion is crucial for developing effective antiviral strategies against FIV infections.

Protein Feline Immunodeficiency Virus Envelope Glycoprotein gp150 (env)
Protein Synonym env; Envelope glycoprotein gp150; Env polyprotein
UniProt ID P16090

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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