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Recombinant Porphyromonas gingivalis Lys-gingipain W83 (kgp), N-His
Product Overview
BioVenic's Recombinant Porphyromonas gingivalis Lys-gingipain W83 (kgp), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 52.4 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Porphyromonas gingivalis Lys-gingipain W83 (kgp) is a virulence factor that plays a significant role in the pathogenesis of periodontal disease. In veterinary medicine, understanding and targeting Kgp can help in developing treatments and preventive strategies against periodontitis in animals, particularly in pets like dogs and cats, which are also susceptible to oral diseases. Kgp contributes to heme and iron acquisition from hemoglobin, which is crucial for the bacterium's survival and virulence. It also plays a role in hemolysis and the degradation of hemoglobin, suggesting its involvement in nutrient acquisition and evasion of the host immune response.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.