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Recombinant Porcine Reproductive and Respiratory Syndrome Virus Non-Structural Protein 4 (PRRSV NSP4), N-His

Cat. No.VG9F50

Product TypeVeterinary Antigens

Size

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Product Overview

BioVenic's Recombinant Porcine Reproductive and Respiratory Syndrome Virus Non-Structural Protein 4 (PRRSV NSP4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 23.4 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Virus
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 23.4 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

Porcine reproductive and respiratory syndrome virus (PRRSV) impacts pigs across all age groups, presenting two interrelated clinical symptoms: reproductive failure in breeding animals and respiratory illness in pigs of any age. The role of Nsp4 in PRRSV replication and pathogenesis has been elucidated, making it a prime molecular target for drug development.

Protein Porcine Reproductive and Respiratory Syndrome Virus Non-Structural Protein 4 (PRRSV NSP4)
Protein Synonym Non-structural protein 4; NSP4; Nonstructural Proteins 4; 3CL
UniProt ID A1E8J1

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -20°C or -80°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in sterile water for a stock solution. Aliquote the reconstituted solution to minimise freeze-thaw cycles.

References

  1. Pathak, Rajesh Kumar et al. "Structural insights into inhibition of PRRSV Nsp4 revealed by structure-based virtual screening, molecular dynamics, and MM-PBSA studies." Journal of biological engineering vol. 16,1 4. 22 Feb. 2022
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