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Recombinant African Swine Fever Virus E184L (E184L CDS), C-His

Name: Recombinant African Swine Fever Virus E184L (E184L CDS), C-His
SKU: VG9C273
Rating: 5 (1 reviews)

Cat. No.VG9C273

Product TypeVeterinary Antigens

Size

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Product Overview

BioVenic's Recombinant African Swine Fever Virus E184L (E184L CDS), C-His is a recombinant protein expressed from Insect Cells. Its predicted molecular weight is 22.7 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein

Species Virus

Expression System Insect Cells

Purity >90% (SDS-PAGE)

Predicted Molecular Weight 22.7 kDa

Physical State Lyophilized

Formulation The buffer before lyophilization is a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

African swine fever virus E184L (E184L CDS) is a key virulence factor that interacts with the innate immune adaptor STING, blocking IFN production, which is crucial for viral replication and pathogenesis. The deletion of E184L from ASFV leads to a reduction in virulence and provides protection against virulent challenges, making it a potential target for developing vaccines that can differentiate infected from vaccinated animals (DIVA). This function is significant in veterinary medicine for controlling the spread of African swine fever.

Protein African Swine Fever Virus E184L (E184L CDS)

Protein Synonym hypothetical protein IM014_gp157; E184L CDS

Gene ID 59227090

UniProt ID A0A2X0RVV9

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.