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Recombinant African Swine Fever Virus CP204L (CP204L), N-His
Product Overview
BioVenic's Recombinant African Swine Fever Virus CP204L (CP204L), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 25.8 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
African swine fever virus CP204L (CP204L) is a multifunctional protein that plays a significant role in the virus's life cycle. It interacts with the VPS39 subunit of the homotypic fusion and vacuole protein sorting complex (HOPS), blocking its association with the lysosomal HOPS complex and modulating endolysosomal trafficking. This interaction promotes lysosome clustering and is crucial for the virus's replication and assembly within the host cell. CP204L is also involved in endosomal trafficking and orchestrates late endosome and lysosome clustering, which is important for the formation of virus factories where viral replication and assembly occur. Understanding the function of CP204L is vital for veterinary medicine as it provides insights into the molecular mechanisms of ASFV pathogenesis and could aid in the development of antiviral strategies and vaccines.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.