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Recombinant Staphylococcus aureus LukF-PV (lukF-PV), N-His

Cat. No.VG9C206

Product TypeVeterinary Antigens

Size

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Product Overview

BioVenic's Recombinant Staphylococcus aureus LukF-PV (lukF-PV), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 36.6 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bacterium
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 36.6 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

Staphylococcus aureus lukF-PV (lukF-PV) is a component of the leukotoxin family, which is crucial in the pathogenesis of bovine mastitis. In veterinary medicine, LukF-PV contributes to the destruction of neutrophils, impairing the innate immune response and leading to severe udder infections. Its role is significant for understanding and combating mastitis in dairy animals, guiding the development of diagnostic tools and vaccines.

Protein Staphylococcus aureus LukF-PV (lukF-PV)
Protein Synonym lukF-PV
UniProt ID O50604

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.

References

  1. Okolie, Charles Emeka. et al. Engineering of the LukS-PV and LukF-PV subunits of Staphylococcus aureus Panton-Valentine leukocidin for diagnostic and therapeutic applications. BMC biotechnology. 2013, 103: 19.
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