Recombinant Bovine Beta-Nerve Growth Factor (NGF), N-His

Bovine beta-nerve growth factor (β-NGF) is a neurotrophin that plays a crucial role in the nervous system's development and maintenance. It is also a seminal plasma protein found in mammals, including cattle, and has been shown to have potent ovulatory and luteotrophic effects when administered systemically. In dairy cattle, β-NGF has been identified as a potential tool to improve reproductive performance, particularly by enhancing luteal function and progesterone production, which are essential for early embryonic survival. It is produced in the ampulla and vesicular glands of bulls and is secreted into the sperm-rich fraction of the ejaculate. The administration of β-NGF has been associated with increased luteal formation, improved endocrine function, and a positive correlation with sire conception rates, making it a significant factor in Bovine reproductive biology.