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Recombinant Swine C-C Motif Chemokine (CCL2), N-His-GST
Product Overview
BioVenic's Recombinant Swine C-C Motif Chemokine (CCL2), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 41.0 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Swine CCL2, also known as Monocyte Chemoattractant Protein-1 (MCP-1), is a small cytokine that plays a pivotal role in recruiting monocytes, memory T cells, and dendritic cells to sites of injured and infected tissue. It is involved in the regulation of immune responses and inflammation, and is critical in controlling autoimmune diseases such as SLE. CCL2 binds to the cell surface receptors C-C motif chemokine receptor 2 (CCR2) and CCR4, mediating its effects on immune cell migration and activation.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.