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Recombinant Bovine Complement C3 (C3), N-His
Product Overview
BioVenic's Recombinant Bovine Complement C3 (C3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 27.8 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Bovine complement C3, a 190 kDa glycoprotein, is a central component of the complement system in cattle, which is crucial for immune defense. It is involved in all three pathways of the complement system: the classical, lectin, and alternative pathways. C3 is activated through proteolysis, leading to the formation of C3b, which covalently binds to immune complexes and invading pathogens, opsonizing them for phagocytosis and clearance.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.