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Recombinant Bovine Pigment Epithelium-Derived Factor (SERPINF1), N-His

Cat. No.AP9C450

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Pigment Epithelium-Derived Factor (SERPINF1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 46.6 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity >95% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 46.6 kDa
Molecular Weight 44 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Bovine pigment epithelium-derived factor (PEDF) is a multifunctional protein primarily isolated from the pigment epithelial cells of the eye. It is known for its potent anti-angiogenic properties and is a major vasoinhibitor that helps maintain the avascular state of the cornea and vitreous body. PEDF also exhibits neurotrophic and neuroprotective activities, playing a role in the survival and differentiation of neurons. In addition to its role in ocular health, PEDF has been shown to have antitumor activity and to regulate lipid metabolism through the activation of the transcription factor PPARα.

Protein Bovine Pigment Epithelium-Derived Factor (SERPINF1)
Protein Synonym SERPINF1; EPC1; PIG35; SDF3; Serpin F1; Cell proliferation-inducing gene 35; Serpin Peptidase Inhibitor,Clade F Member 1(Alpha-2 Antiplasmin); Stromal Cell Derived Factor 3
Gene ID 281386
UniProt ID Q95121

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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