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Recombinant Canine Pyruvate Kinase PKLR (PKLR), N-His
Product Overview
BioVenic's Recombinant Canine Pyruvate Kinase PKLR (PKLR), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Canine pyruvate kinase isozymes R/L (PKLR) are essential for cellular metabolism, catalyzing the conversion of ADP and phosphoenolpyruvate to ATP and pyruvate. This reaction is the final step of glycolysis and is crucial for energy production in dogs. PKLR isozymes are tightly regulated by various allosteric effectors, which control metabolic flux and ATP production. The R-type is specific to red blood cells, while the L-type is found in the liver and kidneys, playing a significant role in maintaining cellular energy homeostasis.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.