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Recombinant Canine Tyrosine-Protein Kinase Receptor (NTRK1), N-His
Product Overview
BioVenic's Recombinant Canine Tyrosine-Protein Kinase Receptor (NTRK1), N-His is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 16.2 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine Tyrosine-Protein Kinase Receptor (NTRK1) is a receptor tyrosine kinase crucial for the development and function of the nervous system in dogs. It regulates neuronal survival, proliferation, and differentiation, particularly in sensory neurons. NTRK1 is activated by nerve growth factor (NGF) and is essential for establishing thermal regulation via sweating. In canines, NTRK1 also plays a role in pain sensation and is involved in the development of the nociceptive system. Dysregulation or mutations in NTRK1 can lead to conditions such as congenital insensitivity to pain with anhidrosis. Additionally, NTRK1 is a potential therapeutic target for pain management and neurodegenerative diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.