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Recombinant Bovine Vascular Endothelial Growth Factor B (VEGFB)
Product Overview
BioVenic's Recombinant Bovine Vascular Endothelial Growth Factor B (VEGFB) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 16.5 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Bovine vascular endothelial growth factor B (VEGFB) is a member of the platelet-derived growth factor (PDGF)/VEGF family. This protein plays a significant role in the regulation of vascular function by binding to VEGF receptors (VEGFRs), influencing angiogenesis, and endothelial cell physiology
. In cattle, VEGFB is involved in the maintenance of vascular health and is expressed in various tissues, including vascular endothelial cells. It has been reported to have both pro-angiogenic and anti-angiogenic effects, depending on the context. For instance, under conditions of tissue disintegration or degeneration, such as in myocardial infarction or neurodegeneration, VEGFB promotes angiogenesis. However, it has also been shown to inhibit tumor angiogenesis and growth in various model systems. The specific role of VEGFB in Bovine is complex and may involve the modulation of immune responses, inflammation, and bone metabolism, as well as its impact on vascular integrity and function.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.