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Recombinant Canine Beta-2-Glycoprotein 1 (APOH)

Cat. No.AP1C52

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine Beta-2-Glycoprotein 1 (APOH) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 40.1 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System E.coli
Purity >95% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 40.1 kDa
Molecular Weight 40.08 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Canine Beta-2-glycoprotein 1 (β2GPI) is a plasma protein that plays a role in immune regulation and blood clotting. It is unique in its ability to both up and down regulate the complement and coagulation systems, which is crucial for maintaining homeostasis. β2GPI is also the primary antigen in antiphospholipid syndrome (APS), an autoimmune condition characterized by thrombosis and pregnancy complications. In dogs, β2GPI may have similar roles in immune response and hemostasis.

Protein Canine Beta-2-Glycoprotein 1 (APOH)
Protein Synonym Apo-H; B2G1; BG; B2-GP1; B2GP1; Autoantigen β2 GP I; Previously; Beta 2 Glycoprotein 1; APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Beta-2-GPI
Gene ID 403945
UniProt ID P33703

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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