This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Feline Potassium Voltage-Gated Channel Subfamily KQT Member 1 (KCNQ1)
Product Overview
BioVenic's Recombinant Feline Potassium Voltage-Gated Channel Subfamily KQT Member 1 (KCNQ1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 65.4 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
In felines, potassium voltage-gated channel subfamily KQT member 1 (KCNQ1) is a crucial voltage-gated potassium channel protein involved in electrophysiological functions in the heart and nervous system. KCNQ1 forms the slow delayed-rectifier potassium current (IKs) in the heart with the auxiliary subunit KCNE1, regulating myocardial repolarization and rhythm. It also participates in potassium recycling in the inner ear to maintain normal hearing. In the gastrointestinal tract and kidneys, KCNQ1 regulates gastric acid secretion and electrolyte balance. Dysfunction of KCNQ1 is associated with diseases like long QT syndrome (LQTS), which can cause arrhythmias and hearing impairments.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.