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Recombinant Ovine C Reactive Protein (CRP), N-His
Product Overview
BioVenic's Recombinant Ovine C Reactive Protein (CRP), N-His is a recombinant protein expressed from E.coli expression system. Its predicted molecular weight is 26.9 kDa. The purity is greater than 90% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It can be used as a positive control or as an immunogen.
Specifications
Target Information
C-Reactive Protein (CRP) serves as a positive acute phase protein (APP). It is a protein produced by the liver. When there's inflammation in the body, the level of CRP increases. CRP plays a crucial role by binding to pathogens, thereby enhancing their opsonizationbefore the specific immunoglobulins (IgM and IgG) are produced. In cattle and sheep, CRP is classified as a moderate APP.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20mM Tris, 150mM NaCl (pH 8.0) to a concentration of 0.1-1.0 mg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Reczyńska, D. et al. Acute Phase Protein Levels as An Auxiliary Tool in Diagnosing Viral Diseases in Ruminants-A Review. Viruses. 2018, 10.