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Recombinant Feline Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha (GADD45A)

Cat. No.AP2C210

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Feline Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha (GADD45A) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 18.4 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Feline
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 18.4 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 6% Trehalose.

Target Information

Feline growth arrest and DNA damage-inducible protein GADD45 Alpha (GADD45A) is a key protein involved in cellular stress responses and DNA repair. In cats, GADD45A is expressed in resting T cells and helps regulate immune responses by inhibiting the alternative p38 activation pathway. It also plays a role in DNA repair and cell cycle regulation, particularly in UV-irradiated cells. Additionally, GADD45A is implicated in the regulation of apoptosis and may influence the production of reactive oxygen species (ROS) in response to oxidative stress. This protein is essential for maintaining genomic stability and preventing autoimmune diseases.

Protein Feline Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha (GADD45A)
Protein Synonym Growth arrest and DNA damage-inducible protein GADD45 alpha
Gene ID 493656
UniProt ID Q60GI5

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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