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Recombinant Feline Cyclin-Dependent Kinase Inhibitor 1 (CDKN1A)

Cat. No.AP2C150

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Feline Cyclin-Dependent Kinase Inhibitor 1 (CDKN1A) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 18.3 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Feline
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 18.3 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 6% Trehalose.

Target Information

In felines, cyclin-dependent kinase inhibitor 1 (CDKN1A, also known as p21) is a key regulator of the cell cycle. It binds to and inhibits cyclin-dependent kinases (CDKs), arresting the cell cycle at the G1 phase and regulating cell proliferation. CDKN1A expression is tightly controlled by the tumor suppressor p53 and plays a crucial role in DNA damage response by inducing cell cycle arrest, facilitating DNA repair, and preventing apoptosis. It also participates in cell differentiation and senescence.

Protein Feline Cyclin-Dependent Kinase Inhibitor 1 (CDKN1A)
Protein Synonym CDK-interacting protein 1
Gene ID 493943
UniProt ID O19002

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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