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Recombinant Canine Coagulation Factor VIII (F8), N-His

Cat. No.AP1C120

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine Coagulation Factor VIII (F8), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 17.9 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System E.coli
Purity >90% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 17.9 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Canine coagulation factor VIII is essential for blood clotting in dogs, functioning as a cofactor in the intrinsic pathway of coagulation that activates factor X. It is part of the complex that includes factor IXa, calcium, and phospholipids, and is vital for hemostasis, particularly in preventing excessive bleeding in conditions like hemophilia A.

Protein Canine Coagulation Factor VIII (F8)
Protein Synonym FVIII; AHF; HEMA; F8B; F8C; Antihemophilic Globulin; Hemophilia A; Anti-Hemophilic Factor A; FVIII Procoagulant Component; F8 Protein
Gene ID 403875
UniProt ID O18806

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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