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Recombinant Mouse Transforming Growth Factor Beta Receptor Type 3 (TGFBR3), C-His
Product Overview
BioVenic's Recombinant Mouse Transforming Growth Factor Beta Receptor Type 3 (TGFBR3), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 93.8 kDa. The purity is>90%.
Specifications
Target Information
Mouse Transforming Growth Factor Beta Receptor Type 3 (TGFBR3), also known as betaglycan, is a ubiquitously expressed, 280 kDa type I transmembrane proteoglycan member of the TGF-beta superfamily of proteins. This receptor often functions as a co-receptor with other TGF-beta receptor superfamily members. TGFBR3 can enhance or inhibit cell signaling. It has been shown to play an essential role in the formation of the atrioventricular cushion and coronary vessels during heart development. TGFBR3 also plays a role in many cancers. Increased expression of TGFBR3 is found in higher grade lymphomas, and reduced expression is associated with advanced stage neuroblastomas and ovarian carcinomas. Low TGFBR3 expression correlates with higher grade breast cancers.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.